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Response of neoplastic and non‐neoplastic cells to a yeast extract
Author(s) -
Fardon John C.,
Poydock M. E.,
Tsuchiya Yoshiki
Publication year - 1978
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930100104
Subject(s) - yeast , in vitro , saccharomyces cerevisiae , ploidy , mitosis , embryo , cell culture , biology , pathology , cancer research , medicine , microbiology and biotechnology , biochemistry , genetics , gene
PCO, an aqueous‐alcoholic extract of the yeast, Saccharomyces cerevisiae, was found to inhibit mitoses of 4 different ascites tumors removed from mice. Carried as established in vitro lines 6 tumors and 4 established lines of non‐neoplastic cells could not be inhibited by PCO. Primary cultures (diploid) of mouse embryo tissue cells and granulocytic blast cells from adult mice also could not be mitotically inhibited by PCO.