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Immunologic reactivity of lymph nodes regional to prostatic cancer: Preliminary observations
Author(s) -
Herr Harry W.
Publication year - 1977
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930090514
Subject(s) - lymph , medicine , lymph node , prostate cancer , immune system , pathology , carcinoma , cancer , prostate , immunology
Regional pelvic lymph nodes from 9 patients with prostatic carcinoma were investigated for in vitro immunologic reactivity to T and B cell mitogens. Regional lymph node lymphocytes were significantly more reactive when obtained from nodes morphologically displaying T and B lymphorplasia than from nodes that histologically appeared normal or depleted of lymphocytes. The data suggest that a morphologic evaluation of lymph nodes regional to prostate cancer may reflect the patient's antitumor immune response.