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Immunocompetence and spontaneous regression of metastatic renal cell carcinoma
Author(s) -
Boasberg Peter D.,
Eilber Frederick R.,
Morton Donald L.
Publication year - 1976
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930080304
Subject(s) - medicine , immunocompetence , renal cell carcinoma , chest radiograph , lung , carcinoma , sensitization , radiology , pathology , immunology , immune system
Spontaneous remission of pulmonary metastases from renal cell carcinoma was correlated with a positive response to dinitrochlorobenzene (DNCB). When first seen, the patient was DNCB negative and a chest radiograph showed nodular densities in the right lung and left midlung. Six months after sensitization, the patient had a positive response to DNCB and no evidence of lung metastases. Three mo later, the patient developed brain metastases although X‐ray examination showed no pulmonary nodules. A diminished response to DNCB was noted over the next several months and chest X ray verified the return of pulmonary metastases.