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Skin test in bronchogenic carcinoma: I. Correlation of the immunological status and the extent of the disease
Author(s) -
Takita Hiroshi,
Brugarolas Antonio
Publication year - 1973
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930050407
Subject(s) - medicine , bronchogenic carcinoma , carcinoma , lymph node metastasis , disease , metastasis , delayed hypersensitivity , skin test , skin reaction , dermatology , surgery , pathology , cancer , immunology , antigen , tuberculosis
Abstract Delayed hypersensitivity reaction of 58 consecutive cases of bronchogenic carcinoma was studied by skin tests. None of the patients with excellent skin reaction was found to have hematogenous metastasis. All patients with negative skin reaction had hematogenous metastasis and all but two such patients died within 2 months. Patients with localized tumors or lymph node metastases appear to maintain competent delayed hypersensitivity reaction and a move toward more aggressive approaches in treating the patients in this group is proposed. It is suggested that skin testing in bronchogenic carcinoma could provide useful information of the extent of the tumor and immunological status of the patients, and should, therefore, be included in routine work‐ups.