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Serum lactic dehydrogenase and isoenzyme changes in clinical cancer
Author(s) -
Wood Don C.,
Varela Virginia,
Palmquist Michele,
Weber Frank
Publication year - 1973
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930050308
Subject(s) - isozyme , medicine , lactic dehydrogenase , disease , gastroenterology , cancer , lactate dehydrogenase , pathology , enzyme , biochemistry , biology
Total LDH and LDH isoenzyme values were measured in serum collected from patients at the time of hospital admission. Changes in isoenzyme values were not necessarily found to depend upon elevated total serum LDH levels. Many patients with normal levels of serum LDH had abnormal isoenzyme patterns usually related to a disease process. A large percentage of patients with neoplastic disease had statistically increased LDH 5 values. Many other patients with either acute and/or chronic disease failed to reflect changes in the isoenzyme values.