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Differential uptake of 125 i − and 99m tco 4 − in a histologically unusual metastatic thyroid carcinoma
Author(s) -
Schall Gerald L.,
Roth Joel A.,
Temple Robert
Publication year - 1973
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930050306
Subject(s) - nuclear medicine , thyroid , medicine , thyroid carcinoma , lymph , iodine , pertechnetate , technetium 99 , epithelioma , carcinoma , technetium , radiochemistry , pathology , chemistry , organic chemistry
A case is presented of a histologically unique thyroid carcinoma metastatic to cervical lymph nodes which concentrated 99m TcO 4 − to a significantly greater degree than 125 I − . This phenomenon may be related to 1. a decreased ability of the tumor to organify iodine, 2. an increased rate of turnover of the iodine‐labeled hormone by the tumor, or 3. the unusual “angiomatoid” pattern of the tumor and the difference in the blood levels of the two tracers at the time of the scans. Hot pertechnetate nodules must be rescanned with radioiodine.