Premium
Experimental bladder carcinogenesis — using cigarette smoke condensate in the rat bladder
Author(s) -
Wagle Datta G.,
Lee Jungeon
Publication year - 1973
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930050302
Subject(s) - carcinogen , medicine , bladder cancer , cigarette smoke , tobacco smoke , smoke , carcinogenesis , population , incidence (geometry) , toxicology , physiology , cancer , environmental health , pathology , waste management , chemistry , biology , biochemistry , optics , engineering , physics
The human and experimental evidence with carcinogenic polynuclear aromatic hydrocarbons and other active products in the genesis of bladder cancer nevertheless demonstrates the urgent need for an epidemiologic analysis of worker groups occupationally exposed to such chemicals. Sections of the general population may also inhale or ingest such chemicals with cigarette smoking or the drinking water polluted with industrial effluents. The present studies noted bladder tumor induction after cigarette smoke condensate exposure. However, the incidence was not great and suggests that time of exposure and other as yet unidentified tumor promoting co‐factors were not present.