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The management of patients with gestational trophoblastic neoplasia based on the antigenic properties of human chorionic gonadotropin
Author(s) -
Goldstein Donald P.,
Nudemberg Franklin,
Lymeburner Nancy,
Levesque Linda,
Shore Christine
Publication year - 1973
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930050102
Subject(s) - medicine , human chorionic gonadotropin , trophoblastic neoplasm , drug , gonadotropin , gynecology , obstetrics , pregnancy , gestation , oncology , pharmacology , hormone , biology , genetics
The use of a rapid, solid‐phase RIA for the quantitative measurement of serum LH‐HCG activity is described for use in the management of patients with GTN. The five‐hour test period permits more precise monitoring of drug therapy without compromising therapeutic effectiveness. The future implications of this new method in redesigning therapeutic regimens according to tumor cell kinetics is discussed.