Premium
Gardner's syndrome, colon cancer, and sarcoma
Author(s) -
Johnson Jerome G.,
Gilbert Enid,
Zimmermann Bernard,
Watne Alvin L.
Publication year - 1972
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930040406
Subject(s) - medicine , fibrosis , sarcoma , colorectal cancer , gardner syndrome , cancer , soft tissue , pathology , bowel obstruction , short bowel syndrome , dermatology , surgery , familial adenomatous polyposis , parenteral nutrition
Soft tissue involvement is a major component of Gardner's syndrome. While these are frequently skin inclusion cysts, some patients exhibit fibrous dysplasias. These can vary from severe fibrosis, frequently intra‐abdominal and causing bowel obstruction, to desmoid tumors and fibrosarcomas, both of which can be progressive and life threatening. This aspect of the syndrome is poorly understood, but must be carefully evaluated in selecting treatment for the associated polyposis coli.