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Cultured human lymphocytes
Author(s) -
Moore George E.
Publication year - 1972
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930040405
Subject(s) - medicine , immunology , lymphocyte , cell , cell culture , antibody , human cell , lymphatic system , cancer research , biology , genetics
Success in establishing human lymphoid cell lines from patients with various genetic, infectious, and malignant disorders and from normal persons has facilitated many new avenues of research. Most lymphoid cell lines seem to remain stable for months and years and can be preserved in cell banks. The cells maintain many specific characteristics and produce at least 10 identifiable cell products. The continuing synthesis of immunoglobulins is of great interest to immunologists. It is possible to culture kilogram quantities of lymphoid cells for biochemical experiments. Large amounts of cells are useful for studies of lymphocyte‐tumor cell interaction and the possible treatment (lymphocytotherapy) of certain infections and malignancies.