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Selenite (Se 75 ) as a tumor‐scanning agent
Author(s) -
Cavalieri Ralph R.,
Steinberg Martin
Publication year - 1971
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930030608
Subject(s) - selenium , medicine , nuclear medicine , chemistry , organic chemistry
Selenite (Se 75 ) is a useful scanning agent for visualization of a wide variety of neoplasms in the brain, skeletal system, and chest. Although tumor specificity is not absolute, this agent shows a relatively high selectivity for lesions containing actively metabolizing cells. Other advantages include ready availability, low cost, long ‘shelf‐life,’ and convenient gamma‐energy spectrum for imaging. The major disadvantage is a relatively long biologic retention, which limits the size of the dose which can be administered. Selenite is recommended, therefore, as a secondary scanning agent, to be used in conjunction with shorter‐lived radiopharmaceuticals. When so used, Se 75 ‐selenite often increases the diagnostic accuracy of scanning procedures.