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Inhibition of lymphocyte blastogenesis by platinum compounds
Author(s) -
Khan Amanullah,
Hill Joseph M.
Publication year - 1971
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930030512
Subject(s) - platinum , medicine , lymphocyte , platinum compounds , immunology , biochemistry , biology , catalysis
The effect of platinum compounds cis ‐platinum (II) diamminodichloride and cis ‐platinum (IV) diamminotetrachloride on the phytohemagglutinin‐induced blastogenesis in lymphocytes was studied. Both compounds inhibited blastogenesis, suggesting that they may be immunosuppressive.