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A new regional perfusion system
Author(s) -
Wilson Samuel E.,
Passaro Edward
Publication year - 1970
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930020210
Subject(s) - pulsatile flow , peristaltic pump , perfusion , medicine , hemolysis , autoregulation , biomedical engineering , cardiology , blood pressure , mechanical engineering , engineering
The development of an in situ perfusion system utilizing a new pulsatile pneumatic pump (Starling‐Fields pump) is described. Experiments with dogs demonstrated that kidneys perfused in situ for 4–6 hr by this system maintained life when transplanted into bilaterally nephrectomized recipients. The pump is automatic and incapable of pumping a gas. A technician is not required for its operation. Hemolysis is less than with roller or peristaltic pumps. The pulsatile flow provided is in the physiologic range. Chemotherapeutic agents may be added easily and directly into the pump. The pump's small size, inability to pump air emboli, autoregulation, low hemolysis, and ease of operation offer advantages that make it especially suitable for regional perfusion use.