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Cytochemical study on the nature of nucleic acids in Epstein—Barr virus (EBV)
Author(s) -
Chai L. S.,
Horoszewicz J. S.,
Grace J. T.
Publication year - 1969
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930010309
Subject(s) - nucleic acid , nucleoid , rnase p , epstein–barr virus , virus , dna , virology , rna , deoxyribonuclease , biology , electron microscope , microbiology and biotechnology , biochemistry , gene , physics , escherichia coli , optics
The nature of nucleic acids present in the nucleoids of Epstein‐Barr virus (EBV) was investigated with cytochemical methods. EBV infected cell cultures were embedded in glycol‐methacrylate and thin sections were exposed to DNase and RNase and examined in the electron microscope. The results showed disappearance of viral nucleoids after DNase treatment, which provided evidence that EBV contains DNA, as do other herpes viruses.