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Immunotherapeutic strategies in breast cancer: A clinical update
Author(s) -
Zhang Jennifer Q.,
Plitas George
Publication year - 2021
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.26287
Subject(s) - medicine , breast cancer , immunotherapy , clinical trial , natural history , oncology , cancer immunotherapy , cancer , blockade , immune system , tumor infiltrating lymphocytes , immunology , receptor
Immunotherapy has been incorporated into the standard of care for a wide range of malignancies. The study of tumor‐infiltrating lymphocytes has emphasized the importance of the host antitumor immune response in the natural history of breast cancer. Recent clinical trials have used immunotherapeutic approaches to augment this response and improve outcomes for patients with breast cancer. Here, we review several current clinical trial data that indicate checkpoint blockade may mediate clinically significant responses.