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Validation process of Toronto Exremity Salvage Score in Italian: A quality of life measure for patients with extremity bone and soft tissue tumors
Author(s) -
Rossi Laura,
Boffano Michele,
Comandone Alessandro,
Ferro Andrea,
Grignani Giovanni,
Linari Alessandra,
Pellegrino Pietro,
Piana Raimondo,
Ratto Nicola,
Davis Aileen M.
Publication year - 2020
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.25849
Subject(s) - medicine , intraclass correlation , quality of life (healthcare) , soft tissue , reliability (semiconductor) , bone sarcoma , construct validity , physical therapy , population , test (biology) , sarcoma , pearson product moment correlation coefficient , surgery , patient satisfaction , psychometrics , pathology , clinical psychology , mathematics , paleontology , power (physics) , physics , nursing , environmental health , quantum mechanics , biology , statistics
Background and Objectives Limb salvage surgery remains the standard treatment in bone and soft tissue tumors. Toronto Extremity Salvage Score (TESS) is the most used quality of life measure. Our objective was to perform cross‐cultural adaptation and validation in Italian, testing test‐retest reliability, construct validity, and responsiveness. Methods We interviewed patients already treated for content validity. A total of 124 patients completed TESS and other questionnaires presurgery, at 3 months, 3 months + 2 weeks, and 6 months follow‐up. We calculated intraclass correlation coefficients (ICCs) for reliability, associations with Pearson's r , and change over time with paired T tests. Results A new item regarding touch‐screen devices was added to the upper extremity (UE) questionnaire. ICC resulted of 0.99 for lower extremity (LE) and 0.98 for UE patients, Pearson's r between TESS and Musculoskeletal Tumor Society was .66 and .64, EuroQol‐5D‐5L r was .62 and .61, and r between TESS and short form‐36 physical function subscale was .76 and .71 for LE and UE groups, respectively. Paired T test results were statistically significant to detect change over time (0.03, 0.04, and 0.04 for LE groups and 0.03, 0.01, and 0.04 for UE groups). Conclusion The Italian version of TESS can be used for the bone and soft tissue sarcoma population in clinical trials in Italy and with Italian speaking patients abroad to ensure patients’ perspectives for efficacy and efficiency of treatments.