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Review of preclinical and clinical studies of using cell‐based therapy for secondary lymphedema
Author(s) -
Chen ChingEn,
Chiang NaiJung,
Perng CherngKang,
Ma Hsu,
Lin ChihHsun
Publication year - 2020
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.25661
Subject(s) - medicine , lymphedema , secondary lymphedema , lymph node , cell therapy , cell , pathology , cancer , breast cancer , genetics , biology
Secondary lymphedema is associated with impaired lymph fluid drainage and remains incurable. Alternatively, cell‐based therapy may pave the way for lymphedema treatment. We found 11 animal and seven human studies had been conducted from 2008 to 2018. Most studies showed great potential for this treatment modality. Emerging studies have focused on novel techniques, such as coupling cell therapy with lymph node transfer, or adding growth factors to cell therapy.