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Historical perspective: Two decades of progress in treating metastatic colorectal cancer
Author(s) -
Lee Rachel M.,
Cardona Kenneth,
Russell Maria C.
Publication year - 2019
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.25431
Subject(s) - medicine , colorectal cancer , disease , stage (stratigraphy) , cancer , oncology , lung cancer , general surgery , intensive care medicine , surgery , paleontology , biology
Colorectal cancer is the third most commonly diagnosed cancer in the United States. While screening methods strive to improve rates of early stage detection, 25% of patients have metastatic disease at the time of diagnosis, with the most common sites being the liver, lung, and peritoneum. While once perceived as hopeless, the last two decades have seen substantial strides in the medical, surgical, and regional therapies to treat metastatic disease offering significant improvements in survival.