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Management of local or regional non‐nodal disease
Author(s) -
Racz Jennifer M.,
Block Matthew S.,
Baum Christian L.,
Jakub James W.
Publication year - 2019
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.25330
Subject(s) - medicine , disease , melanoma , metastasis , lymphatic system , intensive care medicine , general surgery , pathology , cancer , cancer research
Some melanomas develop a striking avidity for lymphatic spread. In spite of multiple recurrences, patients can remain years without visceral metastasis. There is clearly a biologic reason for this lymphotrophic pattern of growth and dissemination, which we have yet to uncover. In‐transit metastases have widely diverse clinical presentations and can be a stubborn disease to cure. As a result, a host of treatments exist that should be tailored to the individual patient.

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