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PET imaging for assessing tumor response to therapy
Author(s) -
Mankoff David A.,
Katz Sharyn I.
Publication year - 2018
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.25114
Subject(s) - positron emission tomography , medicine , molecular imaging , cancer therapy , pet imaging , cancer imaging , targeted therapy , nuclear medicine , cancer , medical physics , in vivo , biology , microbiology and biotechnology
Positron emission tomography (PET) is a radioisotope imaging technique capable of quantifying the regional distribution of molecular imaging probes targeted to biochemical pathways and processes allowing direct measurement of biochemical changes induced by cancer therapy, including the activity of targeted growth pathways and cellular populations. In this manuscript, we review the underlying principles of PET imaging, choices for PET radiopharmaceuticals, methods for tumor analysis and PET applications for cancer therapy response assessment including potential future directions.