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Systemic therapy in retroperitoneal sarcoma management
Author(s) -
Constantinidou Anastasia,
Jones Robin L.
Publication year - 2018
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.24933
Subject(s) - medicine , systemic therapy , sarcoma , chemotherapy , radiology , stage (stratigraphy) , oncology , surgery , pathology , cancer , paleontology , breast cancer , biology
There is paucity of randomized controlled data on the role of systemic therapy in retroperitoneal sarcomas. The type of systemic therapy used is guided by the histological subtype. The majority of retroperitoneal sarcomas comprising liposarcomas and leiomyosarcomas are by and large chemotherapy insensitive. There is an urgent need for more efficacious systemic therapies in the management of early and advanced stage retroperitoneal sarcomas.