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US‐guided core‐needle biopsy versus US‐guided fine‐needle aspiration of suspicious cervical lymph nodes for staging workup of non‐head and neck malignancies: A propensity score matching study
Author(s) -
Ryu Kyeong Hwa,
Lee Jeong Hyun,
Jang Seung Won,
Kim Hwa Jung,
Lee Ji Ye,
Chung Sae Rom,
Chung Mi Sun,
Kim Hyo Weon,
Choi Young Jun,
Baek Jung Hwan
Publication year - 2017
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.24747
Subject(s) - medicine , propensity score matching , retrospective cohort study , confidence interval , head and neck cancer , radiology , odds ratio , logistic regression , lymph , stage (stratigraphy) , cervical lymph nodes , biopsy , fine needle aspiration , neck dissection , univariate analysis , surgery , multivariate analysis , cancer , radiation therapy , pathology , metastasis , biology , paleontology
Background and Objectives To compare US‐guided core‐needle biopsy (USCNB) and US‐guided fine‐needle aspiration (USFNA) of suspicious cervical lymph nodes for staging workup of malignancies in locations other than the head and neck using propensity score matching (PSM). Methods This retrospective cohort study included 108 patients who underwent USFNA and 1058 who underwent USCNB for suspicious cervical lymph nodes detected by imaging modalities during the staging workup for malignancies located in regions other than the head and neck. The primary outcome was defined as the inconclusive results. To evaluate the procedures according to the outcome, we performed univariate and multivariate logistic regression analyses and a 1:1 PSM of USCNB and USFNA. Results There was no complication for both USFNA and USCNB. The inconclusive results were 6.5% (7/108) for USFNA and 1.6% (17/1058) for USCNB. A significantly lower rate of the inconclusive results in USCNB than in USFNA before matching was maintained after a 1:1 PSM of 103 patients from each group (before PSM, odds ratio (OR) = 4.489, 95% confidence interval (CI) [1.803‐11.177], P = 0.001; after PSM, OR = 1.060, 95%CI [1.013‐1.109], P = 0.012). Conclusions Because USCNB can reduce inconclusive results compared to USFNA, it could be more helpful for staging workup of malignancies in locations other than the head and neck in patients with suspicious cervical lymph nodes.