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Surgical strategies and novel therapies for locally advanced pancreatic cancer
Author(s) -
AbouKhalil Jad,
Rocha Flavio G.
Publication year - 2017
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.24654
Subject(s) - medicine , pancreatic cancer , chemotherapy , surgical resection , neoadjuvant therapy , clinical trial , oncology , cancer , surgery , radiology , breast cancer
Many patients with pancreatic cancer are not candidates for surgical resection due to involvement of critical mesenteric vascular structures. We compare and contrast the commonly used classification systems for borderline resectable and locally advanced pancreatic cancer. We describe the current strategies in managing venous and arterial involvement, as well as the role of neoadjuvant chemotherapy and chemoradiation, before explanding on a novel clinical trial in this patient population.