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Multi‐disciplinary management of locally advanced pancreatic cancer with irreversible electroporation
Author(s) -
Martin Robert C.G.
Publication year - 2017
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.24640
Subject(s) - medicine , irreversible electroporation , ablative case , pancreatic cancer , ablation , radiation therapy , radiology , chemotherapy , cancer , surgery , electroporation , biochemistry , chemistry , gene
The essential diagnosis for LAPC is based on high‐quality cross‐sectional imaging, which demonstrates tumor invasion into the celiac/superior mesenteric arteries and/or superior mesenteric/portal venous system that is not reconstructable. The optimal management of these patients is evolving quickly with the advent of newer chemotherapeutics, radiation, and non‐thermal ablation modalities. This review will present the current status of initial chemotherapy, surgical therapy, ablative therapy, and radiation therapy for patients with nonmetastatic locally advanced unresectable pancreatic cancer.