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Global epidemiological trends and variations in the burden of gallbladder cancer
Author(s) -
Are Chandrakanth,
Ahmad Humera,
Ravipati Advaitaa,
Croo Darren,
Clarey Dillon,
Smith Lynette,
Price Ray R.,
Butte Jean M.,
Gupta Sameer,
Chaturvedi Arun,
Chowdhury Sanjib
Publication year - 2017
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.24546
Subject(s) - gallbladder cancer , medicine , demography , china , epidemiology , incidence (geometry) , ethnic group , geography , socioeconomics , environmental health , cancer , pathology , political science , physics , archaeology , sociology , law , optics
BACKGROUND The aim of this study is to describe the trends and variations in the global burden of gallbladder cancer (GBC) with an emphasis on geographic variations and female gender. METHODS Data (2012‐2030) relating to GBC was extracted from GLOBOCAN 2012 database and analyzed. RESULTS The results of our study document a rising global burden of GBC with geographic and gender variations. The highest burden was noted in the WPRO region (based on WHO regions), Asia (based on continents) and India, Chile, and China (based on countries). The less developed regions of the world account for the majority of the global burden of GBC. The geographic variations are also present within individual countries such as in India and Chile. Females are afflicted at a much higher rate with GBC and this predilection is exaggerated in countries with higher incidence such as India and Chile. In females, people of certain ethnic groups and lower socio‐economic standing are at a higher risk. CONCLUSIONS Our study demonstrates a rising global burden of GBC with some specific data on geographic and gender‐based variations which can be used to develop strategies at the global as well as the high‐risk individual country level.