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Chordomas and chondrosarcomas—The role of radiation therapy
Author(s) -
De Amorim Bernstein Karen,
DeLaney Thomas
Publication year - 2016
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.24368
Subject(s) - medicine , radiation therapy , limiting , skull , randomized controlled trial , radiology , surgery , mechanical engineering , engineering
Achieving negative surgical margins can be challenging for skull base and spinal/paraspinal sarcomas. Data shows that pre‐ or post‐operative radiation therapy improves local control. Delivery of sufficient dose of radiation can be difficult because of the proximity to normal organs/tissues that are sensitive to radiation therapy and therefore dose‐limiting. A comprehensive literature search was conducted using PubMed search engine. The scarcity of prospective, randomized data limits the ability to generate definitive treatment recommendations. J. Surg. Oncol. 2016;114:564–569 . © 2016 Wiley Periodicals, Inc.
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