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Racial disparities in esophageal cancer survival after surgery
Author(s) -
Taioli Emanuela,
Wolf Andrea S.,
CamachoRivera Marlene,
Kaufman Andrew,
Lee DongSeok,
Bhora Faiz,
Flores Raja M.
Publication year - 2016
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.24203
Subject(s) - medicine , esophageal cancer , epidemiology , stage (stratigraphy) , esophagus , cancer , hazard ratio , surveillance, epidemiology, and end results , adenocarcinoma , radiation therapy , surgery , carcinoma , cancer registry , confidence interval , paleontology , biology
Objectives Esophageal cancer (EC) black patients have higher mortality rates than Whites. The lower rate of surgery in Blacks may explain the survival difference. We explored the Surveillance Epidemiology and End Results database to determine the impact of surgery on mortality in Blacks and Whites EC. Methods All cases of pathologically proven local and locoregional adenocarcinoma and squamous cell carcinoma of the esophagus from 1973 to 2011 were identified (13,678 White, 2,894 Black patients). Cervical esophageal cancer was excluded. Age, sex, diagnosis year, stage, cancer‐directed surgery, radiation, and vital status were analyzed according to self‐reported race. Results Blacks had higher 1‐year mortality, adjusted for age, sex, stage, year of diagnosis, histology, and therapy [adjusted hazard ratio (HR adj ): 1.24 (95% CI 1.16–1.32)]. Undergoing surgery was an independent predictor of improved survival overall (HR adj 0.30, 95% CI 0.27–0.33). Black patients treated surgically experienced significantly lower survival than Whites, but the difference was not observed in those who did not undergo surgery. Conclusions Although surgery appears to reduce mortality overall, early survival is worse for Blacks. Investigation into racial disparities in health care access and delivery, and to skilled esophageal surgeons is warranted to improve survival for all patients, particularly Blacks. J. Surg. Oncol. 2016;113:659–664 . © 2016 Wiley Periodicals, Inc.