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The importance of surgical margins in retroperitoneal sarcoma
Author(s) -
Kirane Amanda,
Crago Aimee M.
Publication year - 2016
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.24135
Subject(s) - medicine , sarcoma , radiation therapy , surgical resection , gold standard (test) , surgery , resection , histology , retroperitoneal space , margin (machine learning) , radiology , pathology , machine learning , computer science
Surgery is the “gold‐standard” treatment for retroperitoneal sarcomas, but local recurrence is common, and can cause disease‐related death. Complete gross resection is associated with improved survival, but debate exists as to whether resection of adjacent organs to improve margins or prescription of neoadjuvant radiation leads to better outcomes. This review summarizes data addressing prognostic value of margin, extent of surgery necessary to optimize treatment of retroperitoneal sarcomas, and role of histology in optimizing therapy. J. Surg. Oncol. 2016;113:270–276 . © 2015 Wiley Periodicals, Inc.