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The role of margins in extremity soft tissue sarcoma
Author(s) -
Byerly Saskya,
Chopra Shefali,
Nassif Nader A.,
Chen Peter,
Sener Stephen F.,
Eisenberg Burton L.,
Tseng William W.
Publication year - 2016
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.24112
Subject(s) - medicine , soft tissue sarcoma , soft tissue , periosteum , fascia , sarcoma , margin (machine learning) , surgical margin , surgery , resection , pathology , machine learning , computer science
For extremity soft tissue sarcomas, limb salvage is now standard of care. The extent of surgical margins is balanced with functionality of the resected limb. Although negative margins are the goal, the necessary width is unclear. Additional considerations for margin adequacy include presence of anatomic barriers such as fascia and periosteum, proximity of critical structures, receipt of adjuvant and neoadjuvant therapies, and histologic subtype. Multidisciplinary team discussion is critical for treatment planning. J. Surg. Oncol. 2016;113:333–338 . © 2015 Wiley Periodicals, Inc.