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Contemporary diagnostics: Sarcoma pathology update
Author(s) -
Brooks John S.J.,
Lee Solomon
Publication year - 2015
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.23853
Subject(s) - medicine , leiomyosarcoma , sarcoma , pathology , liposarcoma , myoepithelioma , synovial sarcoma , grading (engineering) , rhabdomyosarcoma , immunohistochemistry , civil engineering , engineering , myoepithelial cell
Sarcoma diagnosis continues to evolve as new information is discovered. Certain tumors have been downgraded (dermal leiomyosarcoma) and an atypical category designed for others. Recently entities include myxoinflammatory fibroblastic sarcoma, myoepithelioma, and pseudomyogenic hemangioendothelioma. The terms malignant fibrous histiocytoma and hemangiopericytoma are outdated. New immunostains (STAT6, SOX10, ERG) add diagnostic specificity, and new risk assessment models are described for sarcomas where grading and staging has failed to provide adequate prognosis. J. Surg. Oncol. 2015 111:513–519 . © 2015 Wiley Periodicals, Inc.