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The role of hyperthermic intraperitoneal chemotherapy (HIPEC) and isolated perfusion (ILP) interventions in sarcoma
Author(s) -
Colombo Chiara,
Baratti Dario,
Kusamura Shigeki,
Deraco Marcello,
Gronchi Alessandro
Publication year - 2015
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.23808
Subject(s) - medicine , hyperthermic intraperitoneal chemotherapy , chemotherapy , sarcoma , soft tissue sarcoma , perfusion , hyperthermia , abdominal cavity , peritoneal cavity , intraperitoneal chemotherapy , radiology , cytoreductive surgery , surgery , pathology , cancer , ovarian cancer
Locally advanced sarcomas in the extremity and in the retroperitoneum/abdominal cavity (peritoneal sarcomatosis, PS) can be managed administering chemotherapy locally using isolated limb perfusion (ILP) and hyperthermic intraperitoneal chemotherapy (HIPEC), respectively. In this review, the authors discuss the pros and cons of the use of these locoregional therapies in locally advanced soft tissue sarcoma, with a view to establishing their role in the multidisciplinary approach to these difficult diseases. J. Surg. Oncol. 2015 111:570–579 . © 2014 Wiley Periodicals, Inc.