Premium
Hereditary colorectal cancer syndromes and genetic testing
Author(s) -
Macaron Carole,
Leach Brandie H.,
Burke Carol A.
Publication year - 2015
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.23706
Subject(s) - medicine , colorectal cancer , cancer , genetic testing , genetic counseling , genetic syndromes , lynch syndrome , hereditary cancer , oncology , pediatrics , genetics , dna mismatch repair , breast cancer , biology
Colorectal cancer (CRC) is a leading cause of cancer and cancer deaths in the Western world. Approximately 5–10% of CRC are hereditary, due to a defined genetic cause. Individuals and families affected with a hereditary CRC syndrome exhibit benign and malignant extra‐intestinal tumors, require aggressive cancer screening and benefit from management by a multi‐disciplinary team of professionals. The clinical manifestations, genetic causes and current management of patients with hereditary colon cancer syndrome is provided. J. Surg. Oncol. 2015 111:103–111 . © 2014 Wiley Periodicals, Inc.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom