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Recent insights into the pathophysiology of omental metastases
Author(s) -
Koppe Manuel J.,
Nagtegaal Iris D.,
de Wilt Johannes H.W.,
Ceelen Wim P.
Publication year - 2014
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.23681
Subject(s) - omentectomy , medicine , homing (biology) , greater omentum , metastasis , pathology , surgery , cancer , biology , ecology , hysterectomy
Although, useful in inflammatory conditions, the greater omentum represents an important site of metastasis in peritoneal carcinomatosis and is therefore frequently removed as a staging or therapeutic tool. Apart from the milky spots, omental adipose stem cells, and adipocytes have recently been identified to play a role in the preferential homing of tumor cells to the omentum. The extent of omentectomy and whether a routine omentectomy should be done are still known unknowns. J. Surg. Oncol. 2014 110:670–675 . © 2014 Wiley Periodicals, Inc.