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De novo Stage IV breast cancer: Breast conserving resection of the primary tumor?
Author(s) -
Khan Seema Ahsan
Publication year - 2014
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.23621
Subject(s) - medicine , breast cancer , resection , stage (stratigraphy) , primary tumor , overall survival , oncology , randomized controlled trial , breast tumor , primary treatment , retrospective cohort study , cancer , surgery , metastasis , paleontology , biology
Multiple retrospective reviews completed over the past decade suggest a survival advantage with resection of the intact primary tumor in women with metastatic breast cancer. However, these reviews are not without bias, and recently completed randomized trials do not support a significant survival benefit, although local control benefits may exist. Completion of ongoing trials is needed to reach a definitive conclusion regarding the merit of primary tumor resection for local control and survival. J. Surg. Oncol. 2014 110:51–57 . © 2014 Wiley Periodicals, Inc.