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Locoregional therapies for metastatic colorectal carcinoma to the liver—An evidence‐based review
Author(s) -
Xing Minzhi,
Kooby David A.,
ElRayes Bassel F.,
Kokabi Nima,
Camacho Juan C.,
Kim Hyun S.
Publication year - 2014
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.23619
Subject(s) - medicine , colorectal cancer , metastasis , chemotherapy , oncology , radiology , cancer
The liver is the most common visceral site of colorectal cancer metastasis and recurrence. Given that only 25% of patients with colorectal liver metastases are amenable to curative surgical resection at initial diagnosis, locoregional intra‐arterial therapies including hepatic arterial infusion chemotherapy, conventional transarterial chemoembolization, drug‐eluting‐bead transarterial chemoembolization, and radioembolization have increasingly developed as viable treatment options. The rationale, efficacy, safety, and toxicity of each of these therapies are reviewed and stratified based on current evidence. J. Surg. Oncol. 2014; 110:182–196 . © 2014 Wiley Periodicals, Inc.