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Margins in breast conservation: A clinician's perspective and what the literature tells us
Author(s) -
Houssami Nehmat,
Morrow Monica
Publication year - 2014
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.23594
Subject(s) - medicine , margin (machine learning) , perspective (graphical) , multidisciplinary approach , breast tumor , meta analysis , surgical margin , breast conserving surgery , surgery , oncology , breast cancer , mastectomy , resection , cancer , social science , artificial intelligence , machine learning , sociology , computer science
The optimal margin in breast‐conserving surgery is controversial, and re‐excision is common. Pathologic margin assessment is not standardized, and tumor biology and the use of systemic therapy have a major impact on local control. A study‐level meta‐analysis found no difference in local recurrence for margin widths of 1, 2, and 5 mm, leading a multidisciplinary panel to recommend adoption of no ink on tumor as the standard definition of a negative margin. J. Surg. Oncol. 2014 110:2–7 . © 2014 Wiley Periodicals, Inc.