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Intraperitoneal chemotherapy (IPC) for peritoneal carcinomatosis: Review of animal models
Author(s) -
Gremonprez Félix,
Willaert Wouter,
Ceelen Wim
Publication year - 2014
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.23464
Subject(s) - medicine , intraperitoneal chemotherapy , peritoneal carcinomatosis , chemotherapy , animal model , oncology , intensive care medicine , cancer , colorectal cancer , ovarian cancer
The development of suitable animal models is essential to experimental research on intraperitoneal chemotherapy (IPC). This review of the English literature (MEDLINE) presents a detailed analysis of current animal models and gives recommendations for future experimental research. Special consideration should be given to cytotoxic drug dose and concentration, tumor models, and outcome parameters. J. Surg. Oncol. 2014 109:110–116 . © 2013 Wiley Periodicals, Inc.