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Diagnostic and prognostic significance of serum MicroRNAs in colorectal cancer
Author(s) -
Menéndez Pablo,
Villarejo Pedro,
Padilla David,
Menéndez José M.,
Montes Jose A. Rodríguez
Publication year - 2012
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.23245
Subject(s) - microrna , medicine , colorectal cancer , clinical significance , disease , oncology , cancer , gene , pathology , bioinformatics , genetics , biology
MicroRNAs are short non‐coding RNA molecules involved in the regulation of gene expression. There are few studies related to the determination of serum microRNAs in colorectal cancer. The identification of microRNAs in peripheral blood as noninvasive markers of tumor disease may lead to potential applications, although further clinical studies focusing on serum microRNAs are required to determine their clinical significance for the diagnosis and prognosis outcome of colorectal cancer. J. Surg. Oncol. 2013;107:217–220. © 2012 Wiley Periodicals, Inc.