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A multidisciplinary approach to giant cell tumors of tendon sheath and synovium—A critical appraisal of literature and treatment proposal
Author(s) -
van der Heijden Lizz,
Gibbons C.L. Max H.,
Hassan A. Bass,
Kroep Judith R.,
Gelderblom Hans,
van Rijswijk Carla S.P.,
Nout Remi A.,
Bradley Kevin M.,
Athanasou Nick A.,
Dijkstra P.D. Sander,
Hogendoorn Pancras C. W.,
van de Sande Michiel A. J.
Publication year - 2012
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.23220
Subject(s) - medicine , critical appraisal , multidisciplinary approach , tendon , surgery , pathology , alternative medicine , social science , sociology
Giant cell tumors deriving from synovium are classified into a localized (GCT of tendon sheath; GCT‐TS) and diffuse form (diffuse‐type GCT, Dt‐GCT). We propose a multidisciplinary management based upon a systematic review and authors' opinion. Open excision for GCT‐TS and open synovectomy (plus excision) for Dt‐GCT is advised to reduce the relatively high recurrence risk. External beam radiotherapy should be considered in severe cases, as Dt‐GCT commonly extends extra‐articular. J. Surg. Oncol. 2013;107:433–445. © 2012 Wiley Periodicals, Inc.