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Translation and preliminary validation of the english version of the DUX questionnaire for lower extremity bone tumor patients (Bt‐DUX): A disease‐specific measure for quality of life
Author(s) -
Bekkering W. Peter,
Billing Laura,
Grimer Rob J.,
Vlieland Theodora P.M. Vliet,
Koopman Hendrik M.,
Nelissen Rob G.H.H.,
Taminiau Antonie H.M.
Publication year - 2012
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.23218
Subject(s) - medicine , cronbach's alpha , quality of life (healthcare) , internal consistency , osteosarcoma , physical therapy , surgery , psychometrics , pathology , clinical psychology , patient satisfaction , nursing
Purpose To translate the Dutch DUX questionnaire for lower extremity bone tumor patients (Bt‐DUX), a disease‐specific quality of life (QoL) instrument, into the English (UK) language and preliminary validate the English version in patients who were treated for lower‐extremity bone tumors. Methods Adaptation and translation process included forward translation, back‐translation, and a review of the back‐translation by an expert committee. Internal consistency and validity of the translated questionnaire were examined in a sample of adolescents treated for lower extremity osteosarcoma in the United Kingdom. Assessments included the Bt‐DUX, the Toronto Extremity Salvage Score (TESS), the Short Form (SF)‐36, and the TNO‐AZL Questionnaire for Adult's Quality of Life (TAAQOL). Results Seventeen patients (7 ♂ and 10 ♀), median age 19.9 (range: 16–25) years completed the questionnaires. Mean Bt‐DUX score was 38.8 (range: 23–78), with Cronbach's α being 0.95 domain–total correlations ranged between 0.84 and 0.93 ( P < 0.01). Spearman's correlation coefficients between the Bt‐DUX total and domain scores and corresponding TAAQOL and SF‐36 scores were overall moderate to good and reaching statistical significance in a most cases. Conclusion Preliminary evidence suggests that the English Bt‐DUX translation is a valid disease‐specific instrument for evaluating QoL of adolescents with lower extremity bone cancer. J. Surg. Oncol. 2013;107:353–359. © 2012 Wiley Periodicals, Inc.