Molecular imaging of adrenal neoplasms

The adrenal glands are complex structures from which a variety of benign and malignant tumors may arise and are a common site of metastatic disease. Several radiopharmaceuticals are used for imaging the adrenals, including I‐123/I‐131 metaiodobenzylguanidine (MIBG), norcholesterol derivatives, In‐111 pentetreotide and Ga‐68 somatostatin analogs, [F‐18]fluorodeoxyglucose, [F‐18]fluorodopa, [F‐18]fluorodopamine, C‐11 meta hydroxyephedrine, and C‐11/F‐18/I‐123 Metomidate (MTO) or its analogs. In this review we focus on the role of these reagents in metastatic lesions, cortical neoplasms, pheochromocytoma/paraganglioma, and neuroblastoma (NB). J. Surg. Oncol. 2012; 106:532–542. © 2012 Wiley Periodicals, Inc.