Premium
Routine prophylactic sentinel lymph node biopsy is not indicated in women undergoing prophylactic mastectomy
Author(s) -
Czyszczon Irene Alina,
Roland Lane,
Sahoo Sunati
Publication year - 2011
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.23018
Subject(s) - medicine , sentinel lymph node , axillary lymph node dissection , occult , prophylactic mastectomy , breast cancer , biopsy , mastectomy , lymph , breast carcinoma , surgery , lymph node , carcinoma , sentinel node , cancer , radiology , pathology , alternative medicine
Background Prophylactic mastectomies (PM) are performed to reduce the risk of breast cancer. Occasionally an occult carcinoma is found in PM specimens. Given the high morbidity of axillary lymph node dissection (ALND), some perform prophylactic sentinel lymph node biopsy (SLNB). We undertook a study to examine if prophylactic SLNB is indicated in all patients undergoing PM. Methods A retrospective review of all PM between 2004 and 2010 was performed. The stage of tumor on the disease side and the pathologic findings in the prophylactic breast were analyzed. The number of SLN and the frequency of lymph node metastases were evaluated. Results A total of 199 PM on 184 patients were performed: 169 contralateral PM and 30 bilateral PM. Of the 199 PM, 12 had occult carcinomas (6.0%): 10 non‐invasive, 1 microinvasive and 1 T1b invasive tumor. 153 of 199 PM specimens had prophylactic SLNB, of which only 2 had a positive SLN that originated from the index side of the breast. Conclusions Although it is not uncommon to find occult carcinomas in the prophylactic breast, it is rare for the occult carcinoma to spread to the lymph nodes. Therefore, routine prophylactic SLNB is not indicated in patients undergoing PM. J. Surg. Oncol. 2012; 105:650–654. © 2011 Wiley Periodicals, Inc.