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A retrospective study of surgical treatment of chronic radiation enteritis
Author(s) -
Zhu Weiming,
Gong Jianfeng,
Li Yi,
Li Ning,
Li Jieshou
Publication year - 2011
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.22099
Subject(s) - medicine , radiation enteritis , surgery , anastomosis , perioperative , enterocutaneous fistula , fistula , urinary system , retrospective cohort study , dehiscence , wound dehiscence , parenteral nutrition , concomitant , bowel obstruction , malignancy , radiation therapy , urinary fistula
Background and aims We assessed the role of surgery in the management of patients with intestinal obstruction or enterocutaneous fistula after chronic radiation enteritis (CRE) referred to our department, a specialist gastrointestinal surgical center, and analysis was made for the success of surgery. Methods A retrospective analysis was made of 156 patients receiving radiation therapy for malignancy from Jan 2000 to Nov 2010, among which 134 received surgery for intestinal or urinary complications. The demographic data, nutritional status, previous surgery, disease location and clinical manifestations, concomitant urinary complications, and surgical procedures were analyzed. Results Although malnutrition was prevalent (84/156, 53.9%) in this group of patients, the majority of them (101/134, 75.4%) recovered uneventfully after surgery following nutrition therapy, and resection and anastomosis (102/134) was the predominant surgical procedure for radiation injury to the ileocecal region. Sixteen patients received surgery for radiation‐induced urinary complications. There were 36 postoperative morbidities (26.87%), mainly wound complications (21/134), intestinal obstruction (5/134), and anastomotic dehiscence (3/134). Conclusions Surgery is justified for patients with bowel obstruction or fistula after CRE. A comprehensive perioperative management, especially perioperative nutrition therapy was important for the success of the surgery. J. Surg. Oncol. 2012; 105:632–636. © 2011 Wiley Periodicals, Inc.