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B lymphocytes as effector cells in the immunotherapy of cancer
Author(s) -
Namm Jukes P.,
Li Qiao,
Lao Xiangming,
Lubman David M.,
He Jintang,
Liu Yashu,
Zhu Jianhui,
Wei Shuang,
Chang Alfred E.
Publication year - 2011
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.22093
Subject(s) - effector , medicine , immune system , malignancy , immunotherapy , antigen , immunology , cancer immunotherapy , cancer , antibody , cancer research , pathology
Over the years, the role of B cells in the host immune response to malignancy has been overshadowed by our focus on T cells. Nevertheless, B cells play important roles as antigen‐presenting cells and in the production of antibodies. Furthermore, B cells can function as effector cells that mediate tumor destruction on their own. This review will highlight the various functions of B cells that are involved in the host response to tumor. J. Surg. Oncol. 2012;105:431–435. © 2011 Wiley Periodicals, Inc.