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The quest for diagnostic molecular markers for thyroid nodules with indeterminate or suspicious cytology
Author(s) -
Kouniavsky Guennadi,
Zeiger Martha A.
Publication year - 2012
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.21935
Subject(s) - indeterminate , thyroid nodules , medicine , cytology , fine needle aspiration , thyroid , radiology , pathology , biopsy , mathematics , pure mathematics
Abstract Thyroid nodules are very common and fine needle aspiration (FNA) is a very sensitive means of diagnosis. However, its limitations include the fact that the cytology reports are often indeterminate or suspicious only. The quest for adjunctive measures to improve its specificity has been ongoing for decades, but significant results have remained elusive. The potential use of diagnostic molecular markers appears to be the most promising area of research at this time. J. Surg. Oncol. 2012; 105:438–443. © 2012 Wiley Periodicals, Inc.