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Metabolomics and surgical oncology: Potential role for small molecule biomarkers
Author(s) -
Davis Vanessa W.,
Bathe Oliver F.,
Schiller Daniel E.,
Slupsky Carolyn M.,
Sawyer Michael B.
Publication year - 2010
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.21831
Subject(s) - metabolomics , medicine , omics , precision medicine , cancer , personalized medicine , bioinformatics , molecular biomarkers , translational medicine , oncology , pathology , biology
Metabolomics, the newest of the “omics” sciences, has brought much excitement to the field of oncology as a potential new translational tool capable of bringing the molecular world of cancer care to the bedside. While still early in its development, metabolomics could alter the scope and role of surgery in the multidisciplinary treatment of cancer. This review examines potential roles of metabolomics in areas of early cancer detection, personalized therapeutics and tumorigenesis. J. Surg. Oncol. 2011; 103:451–459. © 2010 Wiley‐Liss, Inc.