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Detection and prognostic impact of micrometastasis in colorectal cancer
Author(s) -
Sirop Saad,
Kanaan Mohammed,
Korant Alpesh,
Wiese David,
Eilender David,
Nagpal Sunil,
Arora Madan,
Singh Trevor,
Saha Sukamal
Publication year - 2011
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.21793
Subject(s) - micrometastasis , medicine , colorectal cancer , oncology , cancer , chemotherapy , metastasis
Review of literature was performed on studies with prognostic impact of micrometastasis in colorectal cancer. Among 16 studies included, micrometastasis was detected in 26.5% of patients. Most analysis revealed that micrometastasis carries a poorer prognosis compared to node negative disease (NND). The results of those studies were compared with our pilot study of 109 patients with colon cancer, showing improved prognosis of micrometastasis after being upstaged and treated with chemotherapy when compared with NND. J. Surg. Oncol. 2011;103:534–537. © 2011 Wiley‐Liss, Inc.