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The extent of lymph node dissection for gastric cancer: A critical appraisal
Author(s) -
de Bree Eelco,
Charalampakis Vasilis,
Melissas John,
Tsiftsis Dimitris D.
Publication year - 2010
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.21646
Subject(s) - medicine , lymphadenectomy , dissection (medical) , critical appraisal , gastrectomy , lymph node , cancer , randomized controlled trial , general surgery , surgery , pathology , alternative medicine
The extent of lymphadenectomy during therapeutic gastrectomy for gastric cancer remains a protracted and controversial issue. While traditionally extended lymphadenectomy is performed in Eastern Asia, limited lymphadenectomy is advocated by most western surgeons. Two large western randomized trials, meta‐analyses and a recent systematic review were unable to demonstrate overall benefit from extended lymphadenectomy. In this review, the currently available data on this topic are critically evaluated, while ongoing studies and future perspective are discussed. J. Surg. Oncol. 2010;102:552–562. © 2010 Wiley‐Liss, Inc.