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Extended lymphadenectomy in the surgery of pancreatic adenocarcinoma and its relation to quality improvement issues
Author(s) -
Rupp Christopher C.,
Linehan David C.
Publication year - 2008
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.21210
Subject(s) - medicine , lymphadenectomy , pancreatic cancer , adenocarcinoma , lymph node , oncology , chemotherapy , pancreatic ductal adenocarcinoma , adjuvant chemotherapy , surgery , general surgery , cancer , breast cancer
Extended lymphadenectomy has been proposed for loco‐regional control of pancreatic adenocarcinoma. While retrospective series suggested a benefit, subsequent prospective trials have not shown a survival benefit. Methods to improve loco‐regional control of pancreatic body/tail cancer have not been extensively investigated. Lymph node status is an important surrogate of survival but is not a driving factor for adjuvant chemotherapy. Quality improvement in pancreatic cancer surgery is discussed, focusing on the impact of lymph nodes in determining prognosis. J. Surg. Oncol. 2009;99:207–214. © 2008 Wiley‐Liss, Inc.