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Sentinel node biopsy for squamous cell carcinoma of the head and neck
Author(s) -
Civantos Francisco,
Zitsch Robert,
Bared Anthony,
Amin Ayman
Publication year - 2008
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.21015
Subject(s) - medicine , sentinel node , biopsy , head and neck , clinical trial , basal cell , head and neck cancer , cancer , melanoma , mucosal melanoma , oncology , carcinoma , radiology , dermatology , surgery , breast cancer , cancer research
The clinical utility of sentinel node biopsy for melanoma has led multiple investigators to apply this approach to other cutaneous malignancies as well as to early cancers of the upper aerodigestive tract. Data are most extensive for oral cancer. A multi‐institutional pathologic validation trial for selected oral cancers provided negative predictive values of 96%. Subsequent trials should document clinical follow‐up. This technique may ultimately play a wider role in the management of mucosal cancers. J. Surg. Oncol. 2008;97:683–690. © 2008 Wiley‐Liss, Inc.